🦟 The Bailey–Dietz Model: Cross-Species Dynamics in Vector-Borne Transmission

šŸ“ˆ Conceptual Overview Vector-borne infectious diseases such as Dengue, Zika, and Malaria require the simultaneous modeling of two biologically distinct populations: a vertebrate host and an arthropod vector. The Bailey–Dietz model extends the classical Ross–Macdonald framework by providing a clear system of ordinary differential equations that explicitly capture the bidirectional transmission cycle between humans and … Read more

šŸŒ”ļø Climate-Sensitive Mechanistic Models: The Core of Vector-Borne Disease Forecasting

Mechanistic (process-based) epidemiological models derived from the Ross–MacDonald framework form the backbone of vector-borne disease forecasting. These models explicitly encode biological and ecological processes and allow climatic drivers—particularly temperature (T) and precipitation (P)—to directly modulate transmission dynamics. By embedding climate-dependent functions into transmission, survival, and incubation processes, these models provide a principled framework for projecting … Read more

🦟 Modeling Dengue Persistence: The Host–Vector–Eggs (HME) Dynamic Framework

The Host–Vector–Eggs (HME) model is a structured extension of the classical Susceptible–Infectious–Susceptible (SIS) and SIR-type formulations, specifically tailored for vector-borne diseases such as Dengue Fever. Its defining feature is the explicit incorporation of the mosquito life cycle, including the egg and immature stages, which play a decisive role in determining adult vector density and, consequently, … Read more

🌐 Beyond the Vector: The 10-Compartment Novel Malaria Model

The Novel Malaria Mathematical Model is an expanded SEIR-based compartmental framework designed to capture malaria transmission through both classical mosquito-borne pathways and non-vector routes such as blood transfusion, congenital transmission, and human-to-human exposure in healthcare settings. By integrating vaccination, treatment, recovery, and multiple exposure mechanisms, this ten-compartment structure provides a comprehensive representation of malaria persistence … Read more

šŸŒ”ļø Modeling Environmental Drivers: The SIR–SI Framework for Vector-Borne Disease

The Susceptible–Infected–Recovered model for humans coupled with a Susceptible–Infected model for mosquitoes (SIR–SI) is a foundational compartmental framework in mathematical epidemiology for studying vector-borne infectious diseases such as malaria. The model explicitly captures the bidirectional transmission dynamics between human hosts and mosquito vectors. A key extension of this framework integrates environmental drivers—most notably temperature and … Read more

🦟 Beyond SIR: Advanced Ross–Macdonald Style Models

Advanced Ross–Macdonald style models constitute the mathematical foundation for understanding and quantifying transmission dynamics of vector-borne diseases, most notably malaria and dengue. These models extend beyond simple SIR-type formulations by explicitly coupling vertebrate host dynamics with insect vector dynamics. Subsequent refinements introduced by later theoretical developments incorporated critical biological realism, including mosquito mortality during the … Read more